Integrative analysis of multiple diverse omics datasets by sparse group multitask regression
نویسندگان
چکیده
منابع مشابه
Integrative analysis of multiple diverse omics datasets by sparse group multitask regression
A variety of high throughput genome-wide assays enable the exploration of genetic risk factors underlying complex traits. Although these studies have remarkable impact on identifying susceptible biomarkers, they suffer from issues such as limited sample size and low reproducibility. Combining individual studies of different genetic levels/platforms has the promise to improve the power and consi...
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High resolution microarrays and second-generation sequencing platforms are powerful tools to investigate genome-wide alterations in DNA copy number, methylation, and gene expression associated with a disease. An integrated genomic profiling approach measuring multiple omics data types simultaneously in the same set of biological samples would render an integrated data resolution that would not ...
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13. CC-BY-NC 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. Abstract 14 Background: The increasing availability of multi-omics datasets has created an opportunity to 15
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2014
ISSN: 2296-634X
DOI: 10.3389/fcell.2014.00062